About the location (from Wiki):
The National Museum in Prague was founded on April 15, 1818, with the first president of the Society of the Patriotic Museum being named Count Sternberk, which would serve as the trustee and operator of the museum. Early on, the focus of the museum was centered on natural sciences, partially because Count Sternberk was a botanist, mineralogist, and eminent phytopaleontologist, but also because of the natural science slant of the times, as perpetrated by Emperor Joseph II of Austria. The main museum building is located on the upper end of Wenceslas Square and was built by prominent Czech neo-renaissance architect Josef Schulz from 1885 – 1891; before this the museum had been temporarily based at several noblemen’s palaces. With the construction of a permanent building for the museum, a great deal of work which had previously been devoted to ensuring that the collections would remain intact was now put toward collecting new materials.

Movies shot at this location:
Ek Shararat UnhE Ko Hai song from Duplicate